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For example, the efficacy of several small molecular targets has been well demonstrated in animal models, such as mGluR5 inhibitors, OT, Memantine, and mTOR inhibitors, but is still unsatisfactory in clinical trials

2025 Sep 3:S1534-5807(25)00530-1

Exposure to human health hazards through direct contact or the food chain must also be considered in order to comprehensively assess the impact of SSRI contamination on ecosystems and to develop relevant regulatory policies to minimize the environmental impact of pharmaceutical agents

[DOI] [PMC free article] [PubMed] [Google Scholar] 233.Seah BC-Q, Teo BM

The mTOR inhibitor effectively restores IL-27-induced excessive activation, proliferation, and secretion of B cells and the abnormal ratio of regulatory B cells to plasma cells in vivo and in vitro [71]

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